Chapter 1 Historical Review of Molecular Biology
1.1 Definition of Molecular Biology
1.2 Brief History of Molecular Biology
1.3 Basic Content of Molecular Biology
1.4 Role of Molecular Biology in Medical Science
Chapter 2 Transmission of Genetic Information
2.1 DNA Replication
2.2 Transcription
2.3 Translation
Chapter 3 Gene Regulation
3.1 Gene Regulation in Prokaryotes
3.2 Gene Regulation in Eukaryotes
3.3 Noncoding RNA and RNA Interference
3.4 Epigenetic Regulation of Gene Expression
3.5 Gene Regulatory Network
Chapter 4 DNA Damage and Repair
4.1 Factors Causing DNA Damage
4.2 Types of DNA Damage
4.3 DNA Repair Mechanisms
4.4 DNA Damage Caused Effects
Chapter 5 Protein Modification, Trafficking and Degradation
5.1 Folding of Nascent Polypeptide Chains
5.2 Assembly of Protein Subunits
5.3 Posttranslational Modifications of Proteins
5.4 Transport and Localization of Proteins
5.5 Degradation of Cellular Proteins
5.6 Clinical Significance of Protein Modification, Trafficking and Degradation
Chapter 6 Molecular Cloning and Genetic Engineering
6.1 Cloning Enzymes
6.2 Cloning Vectors
6.3 Principle and Procedures of Molecular Cloning
6.4 Genetic Engineering
Chapter 7 Gene Characterization and Functional Analysis
7.1 Nucleic Acid Molecular Hybridization
7.2 Polymerase Chain Reaction
7.3 Nucleic Acid Sequencing
Chapter 8 Omics and System Biology
8.1 Genomics
8.2 Transcriptomics
8.3 Proteomics
8.4 Metabolomics
Chapter 9 Gene Transfer and Gene Targeting
9.1 Gene Recombination
9.2 Gene Transfer and Transgenic
9.3 Gene Targeting by Homologous Recombination
9.4 Transgenic and Its Application
Chapter 10 Molecular Biology of Cancer
10.1 Cell Cycle and Apoptosis
10.2 Oncogenes and Tumor Suppressor Genes
10.3 Molecular Basis of Cancer Development
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